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Article

Transcriptional and epigenetic regulation of autophagy in aging

2 Apr 2015

Abstract excerpt

Macroautophagy is a major intracellular degradation process recognized as playing a central role in cell survival and longevity. This multistep process is extensively regulated at several levels, including post-translationally through the action of conserved longevity factors such as the nutrient sensor TOR. More recently, transcriptional regulation of autophagy genes has emerged as an important mechanism for...

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PMID: 25836756
DOI: 10.1080/15548627.2015.1034410

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