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Cell-free DNA analysis in healthy individuals by next-generation sequencing: a proof of concept and technical validation study

11 Jul 2019

Abstract excerpt

Pre-symptomatic screening of genetic alterations might help identify subpopulations of individuals that could enter into early access prevention programs. Since liquid biopsy is minimally invasive it can be used for longitudinal studies in healthy volunteers to monitor events of progression from normal tissue to pre-cancerous and cancerous condition. Yet, cell-free DNA (cfDNA) analysis in healthy individuals...

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PMID: 31296838
DOI: 10.1038/s41419-019-1770-3

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