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Integral membrane protein 2A enhances sensitivity to chemotherapy via notch signaling pathway in cervical cancer

7 Dec 2021

Abstract excerpt

As the second most common cancer among women, cervical cancer is a huge threat to their health all over the world. Integral membrane protein 2A (ITM2A), a member of the Type II Integral Membrane protein (ITM2) family, has been reported to act as a tumor suppressor in breast cancer and ovarian cancer. Moreover, the low expression of ITM2A was associated with cervical adenocarcinoma. However, the function of ITM2A...

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PMID: 34872446
DOI: 10.1080/21655979.2021.2001218

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