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A single nucleotide polymorphism within Ninjurin 2 is associated with risk of multiple sclerosis.

Metabolic brain disease - 1 Oct 2019

Noroozi Rezvan, Azari Iman, Taheri Mohammad, Omrani Mir Davood, Ghafouri-Fard Soudeh

Abstract excerpt

Multiple sclerosis (MS) is a devastating inflammatory disease of the central nervous system (CNS) associated with loss of myelin sheaths. The role of Schwan cells in the remyelination of MS lesions has been documented. However, the detailed steps of this process are unknown. Ninjurin 2 (NINJ2) encodes an adhesion protein with high expression in Schwann cells adjoining the distal piece of injured nerve. Based on...

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Identifiers

PMID: 31292852
DOI: 10.1007/s11011-019-00460-x

Genes

NINJ2

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