Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Replicons of a Rodent Hepatitis C Model Virus Permit Selection of Highly Permissive Cells

10 Jul 2019

Abstract excerpt

A vaccine against hepatitis C virus (HCV) is crucial for global control of this important pathogen, which induces fatal human liver diseases. Vaccine development has been hampered by the lack of immunocompetent animal models. Discovery of rodent hepacivirus (RHV) enabled establishment of novel surrogate animal models. These allow robust infection and reverse genetic and immunization studies of laboratory animals,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis B Virus Studies
Share to Hepatitis C virus research
Share to Influenza Virus Research Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31292246
DOI: 10.1128/jvi.00733-19

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Replicons of a Rodent Hepatitis C Model Virus Permit Selection of Highly Permissive CellsPMID 31292246Read ↗

Viral persistence, liver disease, and host response in a hepatitis C–like virus rat modelSemantic proximity Read ↗

Replication of hepatitis C virus subgenomes in nonhepatic epithelial and mouse hepatoma cells.Semantic proximity Read ↗

Replication of a hepatitis C virus replicon clone in mouse cells.Semantic proximity Read ↗

An immunocompetent murine model of virus-elicited liver fibrosis and hepatocellular carcinomaSemantic proximity Read ↗

On the history of hepatitis C virus cell culture systems.Semantic proximity Read ↗

In vivo models of hepatitis B and C virus infectionSemantic proximity Read ↗

In Vitro Systems for the Study of Hepatitis C Virus InfectionSemantic proximity Read ↗

Development of a Norway Rat Hepacivirus Reporter for High-Throughput Quantification of Neutralising AntibodiesSemantic proximity Read ↗

Generation of a HiBiT-expressing recombinant rat hepacivirus supporting both <i>in vivo</i> and <i>in vitro</i> infectionSemantic proximity Read ↗

HuH-7-Lunet BLR Cells Propagate Rat Hepatitis E Virus (HEV) in a Cell Culture System Optimized for HEVSemantic proximity Read ↗

Robust hepatitis C virus infection <i>in vitro</i>Semantic proximity Read ↗

Cutting the gordian knot-development and biological relevance of hepatitis C virus cell culture systems.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.