[Pathobiology of acute myeloid leukemia].

Abstract excerpt

Acute myeloid leukemia (AML) arises from the clonal expansion of primitive myeloid precursor cells. A series of genetic alterations leads to a perturbation of normal developmental programs affecting growth, maturation and differentiation of hematopoietic cells. As a consequence, immature leukemic cells that have the ability to divide and proliferate, but lack normal differentiation mechanisms, accumulate in the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Leukemia, Myeloid, Acute
• Share to Myeloid Progenitor Cells
• Share to Bone Marrow