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Article

Expression Analysis of RbBP6 in human cancers

8 Jul 2019

Abstract excerpt

Retinoblastoma binding protein 6 (RBBP6) is a cancer-related protein that has been implicated in the regulation of cell cycle and apoptosis. RBBP6 isoform 1 has been demonstrated to interact with two tumour suppressors, p53 and pRB. Isoform 1 been shown to regulate p53 through its ubiquitin ligase activity, thus implicating in cell cycle regulation and apoptosis. Isoforms 1 and 2 are multidomain proteins...

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PMID: 31274515
DOI: 10.1097/cad.0000000000000809

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