Article
Overexpression of RBBP6, alone or combined with mutant TP53, is predictive of poor prognosis in colon cancer.
PloS one - 1 Jan 2013
Chen Jian, Tang Huamei, Wu Zehua, Zhou Chongzhi, Jiang Tao, Xue Yingming, Huang Guoyu, Yan Dongwang, Peng Zhihai
Abstract excerpt
Retinoblastoma binding protein 6 (RBBP6) plays an important role in chaperone-mediated ubiquitination and interacts with TP53 in carcinogenesis. However, the clinicopathologic significance of RBBP6 expression in colon cancer is unknown; in particular, the prognostic value of RBBP6 combined with T...
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