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Article

Elevated Serum SIRT 2 May Differentiate Parkinson’s Disease From Atypical Parkinsonian Syndromes

12 Jun 2019

Abstract excerpt

Atypical Parkinson Syndromes (APSs) often have symptoms that overlap with those of Parkinson's disease (PD), especially in early in disease, making these disorders difficult to diagnose. Previous studies have demonstrated association of oligomeric α-synuclein (α-Syn), a key element in the pathogenesis of PD, with Sirtuin (SIRT)2 proteins for modulating PD. We aimed to evaluate SIRT proteins expression in serum of...

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PMID: 31244600
DOI: 10.3389/fnmol.2019.00129

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