Article

Ultraviolet radiation modulates DNA methylation in melanocytes

2021-10-15

Abstract excerpt

Ultraviolet radiation (UVR) is the principal causal factor for melanoma; albeit the underlying mechanisms remain unclear. While the mutagenic properties of UVR are irrefutable, the role of UVR-induced mutations in the initiation of melanoma is controversial which highlights the gap in our knowledge of the initial critical molecular mechanisms of UVR-induced melanomagenesis. To investigate the potential non-mutatio...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a71b57b4-1ab2-58ae-881c-29b8ea776654
DOI: 10.1101/2021.10.14.464470

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Ultraviolet radiation modulates DNA methylation in melanocytesDOI 10.1101/2021.10.14.464470Read

Ultraviolet light and melanoma.Semantic proximity Read

Deciphering UV‐induced DNA Damage Responses to Prevent and Treat Skin CancerSemantic proximity Read

Concomitant DNA methylation and transcriptome signatures define epidermal responses to acute solar UV radiationSemantic proximity Read

Oxidative Stress and Genotoxicity in Melanoma Induction: Impact on Repair Rather Than Formation of DNA Damage?Semantic proximity Read

Epigenetic and genetic dissections of UV-induced global gene dysregulation in skin cells through multi-omics analysesSemantic proximity Read

Further assessment of exome-wide UVR footprints in melanoma and their possible relevance.Semantic proximity Read

Ultraviolet radiation drives mutations in a subset of mucosal melanomas.Semantic proximity Read

Current Insights into the Role of UV Radiation-Induced Oxidative Stress in Melanoma PathogenesisSemantic proximity Read

Epigenetics and Ultraviolet Radiation: Implications for Skin Ageing and CarcinogenesisSemantic proximity Read

UV Radiation and Its Relation to DNA Methylation in Epidermal Cells: A ReviewSemantic proximity Read

Cutaneous and acral melanoma cross-OMICs reveals prognostic cancer drivers associated with pathobiology and ultraviolet exposureSemantic proximity Read

Skin Photodamage and Melanomagenesis: A Comprehensive ReviewSemantic proximity Read