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Interplay between ROS and Autophagy in Cancer and Aging: From Molecular Mechanisms to Novel Therapeutic Approaches

4 Aug 2019

Abstract excerpt

Aging and cancer are highly related biological phenomena. Cellular processes that underpin several malignant phenotypic traits, including DNA damage responses, oxidative stress, metabolic rewiring, and cellular senescence, also contribute to aging. Reactive oxygen species (ROS) play an essential role as intra- and extracellular messengers, orchestrating functional and metabolic states of the cell through the...

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PMID: 31467639
DOI: 10.1155/2019/8794612

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