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Article

Nonalcoholic fatty liver disease and eGFR levels could be linked by the PNPLA3 I148M polymorphism in children with obesity

11 Jun 2019

Abstract excerpt

BACKGROUND: PNPLA3 I148M polymorphism has an effect on modulation of estimated glomerular filtration rate (eGFR) in nonobese nondiabetic adults and in children with histologically confirmed nonalcoholic fatty liver disease (NAFLD). OBJECTIVES: The objective of the study is to explore the impact of PNPLA3 I148M polymorphism on eGFR in children with obesity with and without NAFLD. METHODS: We genotyped 591 patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31184438
DOI: 10.1111/ijpo.12539

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Nonalcoholic fatty liver disease and eGFR levels could be linked by the PNPLA3 I148M polymorphism in children with obesityPMID 31184438Read ↗

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I148M variant in PNPLA3 reduces central adiposity and metabolic disease risks while increasing nonalcoholic fatty liver disease.Semantic proximity Read ↗

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Influence of genetics on clinical trajectories in children with MASLD: role of the PNPLA3 I148M polymorphism.Semantic proximity Read ↗

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