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Article

Aging‐induced Akt activation involves in aging‐related pathologies and Aβ‐induced toxicity

11 Jun 2019

Abstract excerpt

Multicellular signals are altered in the processes of both aging and neurodegenerative diseases, including Alzheimer's disease (AD). Similarities in behavioral and cellular functional changes suggest a common regulator between aging and AD that remains undetermined. Our genetics and behavioral approaches revealed the regulatory role of Akt in both aging and AD pathogenesis. In this study, we found that the...

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PMID: 31183966
DOI: 10.1111/acel.12989

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