Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population.

doi:10.1038/s42003-021-02056-7

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population.

Communications biology - 3 May 2021

Chang Xuling, Gurung Resham L, Wang Ling, Jin Aizhen, Li Zheng, Wang Renwei, Beckman Kenneth B, Adams-Haduch Jennifer, Meah Wee Yang, Sim Kar Seng, Lim Weng Khong, Davila Sonia, Tan Patrick, Teo Jing Xian, Yeo Khung Keong, M Yiamunaa, Liu Sylvia, Lim Su Chi, Liu Jianjun, van Dam Rob M, Friedlander Yechiel, Koh Woon-Puay, Yuan Jian-Min, Khor Chiea Chuen, Heng Chew-Kiat, Dorajoo Rajkumar

Abstract excerpt

The role of low frequency variants associated with telomere length homeostasis in chronic diseases and mortalities is relatively understudied in the East-Asian population. Here we evaluated low frequency variants, including 1,915,154 Asian specific variants, for leukocyte telomere length (LTL) associations among 25,533 Singapore Chinese samples. Three East Asian specific variants in/near POT1, TERF1 and STN1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cross-Sectional Studies

Share to Leukocytes

Share to Neoplasms

Share to Shelterin Complex

Share to Singapore

Share to Telomere-Binding Proteins

Share to Telomere Homeostasis

Source

Open in PubMed Open full text

Identifiers

PMID: 33941849
DOI: 10.1038/s42003-021-02056-7
PMCID: PMC8093266

Genes

POT1
STN1

Variants

Rs79314063

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population.PMID 33941849Read ↗

Loci for human leukocyte telomere length in the Singaporean Chinese population and trans-ethnic genetic studiesSemantic proximity Read ↗

Genetic and clinical determinants of telomere lengthSemantic proximity Read ↗

Genomic, phenomic, and geographic associations of leukocyte telomere length in the United StatesSemantic proximity Read ↗

Genomic, phenomic and geographic associations of leukocyte telomere length in the United States.Semantic proximity Read ↗

The enigma of excessively long telomeres in cancer: lessons learned from rare human POT1 variantsSemantic proximity Read ↗

Common variants near TERC are associated with leukocyte telomere length in the Chinese Han population.Semantic proximity Read ↗

Genetic variation in telomere maintenance genes, telomere length, and lung cancer susceptibility.Semantic proximity Read ↗

A genome-wide association study identifies a locus on TERT for mean telomere length in Han Chinese.Semantic proximity Read ↗

Single Nucleotide Polymorphisms Related to Telomere Length Predispose for Coronary Heart Disease in Chinese Han PopulationSemantic proximity Read ↗

Identification of seven loci affecting mean telomere length and their association with disease.Semantic proximity Read ↗

Genome-wide association study of telomere length among South Asians identifies a second RTEL1 association signal.Semantic proximity Read ↗

Telomere Length as a New Risk Marker of Early-Onset Colorectal CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.