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Article

Airway host-microbiome interactions in chronic obstructive pulmonary disease

6 Jun 2019

Abstract excerpt

BACKGROUND: Little is known about the interactions between the lung microbiome and host response in chronic obstructive pulmonary disease (COPD). METHODS: We performed a longitudinal 16S ribosomal RNA gene-based microbiome survey on 101 sputum samples from 16 healthy subjects and 43 COPD patients, along with characterization of host sputum transcriptome and proteome in COPD patients. RESULTS: Dysbiosis of sputum...

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PMID: 31170986
DOI: 10.1186/s12931-019-1085-z

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