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Article

Microbiome-host interactions in the pathogenesis of acute exacerbation of chronic obstructive pulmonary disease

18 Jul 2024

Abstract excerpt

Objective To explore the underlying mechanisms the airway microbiome contributes to Acute Exacerbation of Chronic Obstructive Pulmonary Disease(AECOPD). Methods We enrolled 31 AECOPD patients and 26 stable COPD patients, their sputum samples were collected for metagenomic and RNA sequencing, and then subjected to bioinformatic analyses. The expression of host genes was validated by Quantitative Real-time...

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Chronic Obstructive Pulmonary Disease (COPD) Research
Gut microbiota and health
Pediatric health and respiratory diseases

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39091676
DOI: 10.3389/fcimb.2024.1386201

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