Article
Lung microbiome dynamics in COPD exacerbations.
The European respiratory journal - 1 Apr 2016
Wang Zhang, Bafadhel Mona, Haldar Koirobi, Spivak Aaron, Mayhew David, Miller Bruce E, Tal-Singer Ruth, Johnston Sebastian L, Ramsheh Mohammadali Yavari, Barer Michael R, Brightling Christopher E, Brown James R
Abstract excerpt
Increasing evidence suggests that the lung microbiome plays an important role in chronic obstructive pulmonary disease (COPD) severity. However, the dynamics of the lung microbiome during COPD exacerbations and its potential role in disease aetiology remain poorly understood.We completed a longitudinal 16S ribosomal RNA survey of the lung microbiome on 476 sputum samples collected from 87 subjects with COPD at...
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