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Article

Significance of PTEN Mutation in Cellular Process, Prognosis, and Drug Selection in Clear Cell Renal Cell Carcinoma

8 May 2019

Abstract excerpt

It is well established that the PTEN (Phosphatase and Tensin Homolog) mutant is a frequently mutated gene found in clear cell renal cell carcinoma (ccRCC), making it a potential biomarker for individualized treatment opinions. Here, in the present study, we designed a method to evaluate the significance of the PTEN mutation in the prognosis and drug selection of ccRCC, determine the potential changing pathways...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31139560
DOI: 10.3389/fonc.2019.00357

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