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Overexpression of PLCG2 and TMEM38A inhibit tumor progression in clear cell renal cell carcinoma

25 Jan 2025

Abstract excerpt

Clear cell renal cell carcinoma is a prevalent urological malignancy, imposing substantial burdens on both patients and society. In our study, we used bioinformatics methods to select four putative target genes associated with EMT and prognosis and developed a nomogram model which could accurately predicting 5-year patient survival rates. We further analyzed proteome and single-cell data and selected PLCG2 and...

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PMID: 39863641
DOI: 10.1038/s41598-025-86644-1

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