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Article

Mining tissue microarray data to uncover combinations of biomarker expression patterns that improve intermediate staging and grading of clear cell renal cell cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jan 2010

Dahinden Corinne, Ingold Barbara, Wild Peter, Boysen Gunther, Luu Van-Duc, Montani Matteo, Kristiansen Glen, Sulser Tullio, Bühlmann Peter, Moch Holger, Schraml Peter

Abstract excerpt

PURPOSE: Tumor stage and nuclear grade are the most important prognostic parameters of clear cell renal cell carcinoma (ccRCC). The progression risk of ccRCC remains difficult to predict particularly for tumors with organ-confined stage and intermediate differentiation grade. Elucidating molecular pathways deregulated in ccRCC may point to novel prognostic parameters that facilitate planning of therapeutic...

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PMID: 20028743
DOI: 10.1158/1078-0432.CCR-09-0260

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