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Article

Is the Complement Protein C1q a Pro- or Anti-tumorigenic Factor? Bioinformatics Analysis Involving Human Carcinomas

3 May 2019

Abstract excerpt

C1q is the first subcomponent of the classical pathway of the complement system and belongs to the C1q/Tumour Necrosis Factor superfamily. In addition, C1q can perform a diverse range of immune and non-immune functions in a complement-dependent as well as -independent manner. Being a charge pattern recognition molecule of the innate immunity, C1q can recognise a number of self, non-self and altered-self ligands...

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Identifiers

PMID: 31130944
DOI: 10.3389/fimmu.2019.00865

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