Article
Historical review: more than two decades understanding the genetic architecture of hemostasis and thrombosis.
Journal of thrombosis and haemostasis : JTH - 1 Mar 2026
Sabater-Lleal Maria, Thibord Florian, de Vries Paul S, Huffman Jennifer, Wolberg Alisa S, Lowenstein Charles J, Morrison Alanna C, Johnson Andrew D, Smith Nicholas L
Abstract excerpt
From the beginning of the millennium and the development of genome-wide analyses, the technical advances and remarkable increase in research sample sizes have led to an escalating number of discoveries revealing genetic determinants of levels of the main factors regulating hemostasis and thrombosis and demonstrating a clear polygenic complex regulation of most coagulation factors. These discoveries have been...
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