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Silent mysteries: epigenetic paradigms could hold the key to conquering the epidemic of allergy and immune disease

1 Oct 2009

Abstract excerpt

Epigenetic mechanisms provide new insights into how environmental changes may mediate the increasing propensity for complex immune diseases such as allergic disease. There is now strong evidence that early environmental exposures play a key role in activating or silencing genes by altering DNA and histone methylation, histone acetylation and chromatin structure. These modifications determine the degree of DNA...

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PMID: 19796189
DOI: 10.1111/j.1398-9995.2009.02186.x

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