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Article

Genomic Mismatch at LIMS1 Locus and Kidney Allograft Rejection

15 May 2019

Abstract excerpt

BACKGROUND: In the context of kidney transplantation, genomic incompatibilities between donor and recipient may lead to allosensitization against new antigens. We hypothesized that recessive inheritance of gene-disrupting variants may represent a risk factor for allograft rejection. METHODS: We performed a two-stage genetic association study of kidney allograft rejection. In the first stage, we performed a...

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PMID: 31091373
DOI: 10.1056/nejmoa1803731

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