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Genomic and Transcriptomic Characterization Links Cell Lines with Aggressive Head and Neck Cancers

1 Oct 2018

Abstract excerpt

Cell lines are important tools for biological and preclinical investigation, and establishing their relationship to genomic alterations in tumors could accelerate functional and therapeutic discoveries. We conducted integrated analyses of genomic and transcriptomic profiles of 15 human papillomavirus (HPV)-negative and 11 HPV-positive head and neck squamous cell carcinoma (HNSCC) lines to compare with 279 tumors...

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Identifiers

PMID: 30380422
DOI: 10.1016/j.celrep.2018.10.007

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