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Article

High methylation levels of PCDH10 predict poor prognosis in patients with pancreatic ductal adenocarcinoma

14 May 2019

Abstract excerpt

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies and is not a clinically homogeneous disease, but subsets of patients with distinct prognosis and response to therapy can be identified by genome-wide analyses. Mutations in major PDAC driver genes were associated with poor survival. By bioinformatics analysis, we identified protocadherins among the most frequently mutated...

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PMID: 31088413
DOI: 10.1186/s12885-019-5616-2

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