Article
Role of gene promoter methylation regulated by TETs and DNMTs in the overexpression of HLA‑G in MCF‑7 cells
11 Apr 2019
Abstract excerpt
Human leukocyte antigen-G (HLA-G) is highly expressed in numerous solid tumor cell types and has important roles in protecting tumor cells from host immune recognition and destruction. DNA methylation modification, which may regulate gene expression, is aberrant in numerous tumor cell types. However, whether the high expression of HLA-G in tumor cells is induced by aberrant DNA methylation has remained elusive....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.