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Npat ‐dependent programmed Sertoli cell proliferation is indispensable for testis cord development and germ cell mitotic arrest

14 May 2019

Abstract excerpt

ABSTRACT As the major somatic cell type, Sertoli cells undergo active proliferation and play essential roles to establish testis cord at fetal stage. They also function to maintain germ cell development throughout the life of testicular development. However, the significance of Sertoli cell number for testis cord development and gonocyte fate is still unclear. Nuclear protein ataxia‐telangiectasia (NPAT, also...

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PMID: 31084574
DOI: 10.1096/fj.201802289rr

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