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Is the Adult Sertoli Cell Terminally Differentiated?1

5 Apr 2012

Abstract excerpt

New data have challenged the convention that the adult Sertoli cell population is fixed and unmodifiable. The Sertoli cell has two distinct functions: 1) formation of the seminiferous cords and 2) provision of nutritional and structural support to developing germ cells. For these to occur successfully, Sertoli cells must undergo many maturational changes between fetal and adult life, the main switches occurring...

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PMID: 22492971
DOI: 10.1095/biolreprod.111.095091

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