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Article

Global deletion of Optineurin results in altered type I IFN signaling and abnormal bone remodeling in a model of Paget’s disease

10 May 2019

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 31076632
DOI: 10.1038/s41418-019-0341-6

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Global deletion of Optineurin results in altered type I IFN signaling and abnormal bone remodeling in a model of Paget’s diseasePMID 31076632Read ↗

Optineurin regulates osteoblast function in an age-dependent fashion in a mouse model of Paget's disease of boneSemantic proximity Read ↗

Optineurin Negatively Regulates Osteoclast Differentiation by Modulating NF-κB and Interferon Signaling: Implications for Paget’s DiseaseSemantic proximity Read ↗

Cellular Functions of Optineurin in Health and Disease.Semantic proximity Read ↗

Toward an integrative view of Optineurin functionsSemantic proximity Read ↗

Optineurin Insufficiency Disbalances Proinflammatory and Anti-inflammatory Factors by Reducing Microglial IFN-β ResponsesSemantic proximity Read ↗

Critical role for inflammasome-independent IL-1β production in osteomyelitis.Semantic proximity Read ↗

Genome-wide association identifies three new susceptibility loci for Paget's disease of bone.Semantic proximity Read ↗

Bone: Do all Paget disease risk genes incriminate the osteoclast?Semantic proximity Read ↗

Increased neutrophil infiltration, IL-1 production and a SAPHO syndrome-like phenotype in PSTPIP2-deficient mice.Semantic proximity Read ↗

Loss of optineurin in vivo results in elevated cell death and alters axonal trafficking dynamics.Semantic proximity Read ↗

Targeted Ptpn11 deletion in mice reveals the essential role of SHP2 in osteoblast differentiation and skeletal homeostasisSemantic proximity Read ↗

Molecular effect of an OPTN common variant associated to Paget's disease of bone.Semantic proximity Read ↗

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