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Article

BMP4-mediated brown fat-like changes in white adipose tissue alter glucose and energy homeostasis.

Proceedings of the National Academy of Sciences of the United States of America - 26 Feb 2013

Qian Shu-Wen, Tang Yan, Li Xi, Liu Yuan, Zhang You-You, Huang Hai-Yan, Xue Rui-Dan, Yu Hao-Yong, Guo Liang, Gao Hui-Di, Liu Yan, Sun Xia, Li Yi-Ming, Jia Wei-Ping, Tang Qi-Qun

Abstract excerpt

Expression of bone morphogenetic protein 4 (BMP4) in adipocytes of white adipose tissue (WAT) produces "white adipocytes" with characteristics of brown fat and leads to a reduction of adiposity and its metabolic complications. Although BMP4 is known to induce commitment of pluripotent stem cells to the adipocyte lineage by producing cells that possess the characteristics of preadipocytes, its effects on the...

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Identifiers

PMID: 23388637
DOI: 10.1073/pnas.1215236110
PMCID: PMC3587258

Genes

BMP4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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