Article
Peptides containing the cell-attachment recognition signal Arg-Gly-Asp prevent gastrulation in Drosophila embryos.
Nature - 1 Jan 2000
Naidet C, Sémériva M, Yamada K M, Thiery J P
Abstract excerpt
It has recently been suggested that the Arg-Gly-Asp sequence (RGD) forms part of a widespread cell-extracellular matrix recognition system. Analysis of the cell binding sites of vertebrate fibronectin and other extracellular proteins that interact with cell surfaces implicate the same amino acid...
Topics
- Amino Acid Sequence
- Animals
- Cell Adhesion
- Drosophila melanogaster
- Gastrula
- Morphogenesis
- Mutation
- Oligopeptides