Article
Fibronectin matrix composition and organization can regulate cell migration during amphibian development.
Mechanisms of development - 1 Apr 2000
Darribère T, Schwarzbauer J E
Abstract excerpt
Fibronectin (FN) is an adhesive extracellular matrix component that is essential for vertebrate development. It forms a fibrillar matrix at the cell surface which controls cell morphology, migration, proliferation, and other important cellular processes. To address specific functions of FN matrix structure during early vertebrate development, we introduced normal and mutant recombinant FNs (recFNs) into the...
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