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Complement Therapeutics in Autoimmune Disease

3 Apr 2019

Abstract excerpt

Many autoimmune diseases are characterized by generation of autoantibodies that bind to host proteins or deposit within tissues as a component of immune complexes. The autoantibodies can activate the complement system, which can mediate tissue damage and trigger systemic inflammation. Complement inhibitory drugs may, therefore, be beneficial across a large number of different autoimmune diseases. Many new...

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PMID: 31001274
DOI: 10.3389/fimmu.2019.00672

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