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Article

Bax Targeted by miR-29a Regulates Chondrocyte Apoptosis in Osteoarthritis

12 Mar 2019

Abstract excerpt

Osteoarthritis (OA) is a chronic degenerative joint disease, where chondrocyte apoptosis is responsible for cartilage degeneration. Bax is a well-known proapoptotic protein of the Bcl-2 family, involved in a large number of physiological and pathological processes. However, the regulation mechanisms of Bax underlying chondrocyte apoptosis in OA remain unknown. In the present study, we determined the role of Bax...

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PMID: 30993110
DOI: 10.1155/2019/1434538

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