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Identification of 19 Novel Hepatitis C Virus Subtypes—Further Expanding HCV Classification

22 Feb 2019

Abstract excerpt

BACKGROUND: Hepatitis C virus (HCV) is currently classified into 8 genotypes and 86 subtypes. The objective of this study was to characterize novel HCV subtypes and to investigate the impact of subtypes on treatment outcome. METHODS: Full-genome sequencing was performed on HCV plasma samples with <85% sequence homology of NS3, NS5A, and/or NS5B to HCV genotype (GT) 1-8 reference strains. RESULTS: A total of 14...

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PMID: 30949527
DOI: 10.1093/ofid/ofz076

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