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Article

Characterization of a Novel Hepatitis C Subtype, 6xj, and Its Consequences for Direct-Acting Antiviral Treatment in Yunnan, China.

Microbiology spectrum - 3 Sept 2021

Jia Yuanyuan, Yue Wei, Gao Qinghua, Tao Rui, Zhang Yaxiang, Fu Xiaoyang, Liu Yang, Liu Li, Feng Yue, Xia Xueshan

Abstract excerpt

Hepatitis C virus (HCV) has a high rate of genetic variability, with eight genotypes and 91 subtypes. The genetic diversity of HCV genotype 6 (HCV-6) is the highest with 31 subtypes, and this genotype is prevalent in Southeast Asia. In this study, we investigated 160 individuals with chronic hepatitis C in Yunnan Province, China. Using reverse transcription (RT)-PCR and Sanger sequencing, 147 cases were...

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Identifiers

PMID: 34479413
DOI: 10.1128/Spectrum.00297-21
PMCID: PMC8552672

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