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Article

Differential effects of antiepileptic drugs on human bone cells

2 Apr 2019

Abstract excerpt

Antiepileptic drugs (AED) have been associated to in vivo deleterious consequences in bone tissue. The present work aimed to characterize the cellular and molecular effects of five different AED on human osteoclastogenesis and osteblastogenesis. It was observed that the different drugs had the ability to differentially modulate both processes, in a way dependent on the identity and dose of the AED. Shortly,...

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PMID: 30941778
DOI: 10.1002/jcp.28569

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