Article
The effect of gabapentin-lactam hydroxamic acid derivatives on ovine osteoblast proliferation and phenotype: perspectives for tissue engineering application.
The International journal of oral & maxillofacial implants - 1 Jan 2000
Duttenhoefer Fabian, Fuessinger Marc Anton, Ahne Sieglinde, Oshima Toshiyuki, Gutwald Ralf, Schmelzeisen Rainer, Sauerbier Sebastian
Abstract excerpt
PURPOSE: Modern bone tissue engineering associated with mesenchymal stem cells (MSCs) provides promising treatment alternatives for the loss of bone, one of the foremost challenges in oral and craniofacial surgery today. The effect of gabapentin-lactam (GBP-L) and its analogs on osteogenic differentiated MSCs has not yet been deciphered. Consequently, this study investigates the effect of novel...
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