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Article

Data-Driven Discovery of a Key Regulator Cyclin A2 as a Promising Therapeutic Target in Hormone-Sensitive Cancers.

Molecular biotechnology - 1 May 2026

Anbarasu Suvitha, Anbarasu Anand

Abstract excerpt

Hormone-sensitive cancers (HSCs) are one of the predominant types of cancer leading to death globally. The current study has attempted to discover a potential therapeutic target that could be used against HSCs in women, namely, breast, ovarian, and endometrial cancer. The differentially expressed genes in each cancer type were compared with previously reported tamoxifen resistance-causing genes. The hub genes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Neoplastic

Share to ISG15 gene

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Source

Identifiers

PMID: 40936038
DOI: 10.1007/s12033-025-01504-7

Genes

CCNA2
CDCA8
E2F1
CDKN3
CENPE
CXCR4
ISG15
LYN
MYBL2
NEK2
POLE2
PRC1
ZWINT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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