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Cell-Free DNA as a Biomarker in Autoimmune Rheumatic Diseases

19 Mar 2019

Abstract excerpt

Endogenous DNA is primarily found intracellularly in nuclei and mitochondria. However, extracellular, cell-free (cf) DNA, has been observed in several pathological conditions, including autoimmune diseases, prompting the interest of developing cfDNA as a potential biomarker. There is an upsurge in studies considering cfDNA to stratify patients, monitor the treatment response and predict disease progression, thus...

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PMID: 30941136
DOI: 10.3389/fimmu.2019.00502

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