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Article

Heterogeneity of the Human Pancreatic Islet

1 Apr 2019

Abstract excerpt

Pancreatic β-cells play a pivotal role in maintaining normoglycemia. Recent studies have revealed that the β-cell is not a homogeneous cell population but, rather, is heterogeneous in a number of properties such as electrical activity, gene expression, and cell surface markers. Identification of specific β-cell subpopulations altered in diabetic conditions would open a new avenue to develop targeted therapeutic...

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PMID: 30936150
DOI: 10.2337/db19-0072

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