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Metallothionein Genes are Highly Expressed in Malignant Astrocytomas and Associated with Patient Survival

1 Apr 2019

Abstract excerpt

Gliomas are heterogeneous, primary brain tumours that originate from glial cells. The main type of gliomas is astrocytomas. There are four grades (I-IV) of astrocytoma malignancy. Astrocytoma grade IV known as glioblastoma multiforme (GBM) is the most common and aggressive type of astrocytic gliomas. Metallothioneins (MT) are low molecular weight, cysteine rich proteins encoded by a family of metallothionein (MT)...

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PMID: 30932010
DOI: 10.1038/s41598-019-41974-9

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