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Article

WT1 expression increases with malignancy and indicates unfavourable outcome in astrocytoma.

Journal of clinical pathology - 1 Jul 2014

Rauscher Julian, Beschorner Rudi, Gierke Midea, Bisdas Sotirios, Braun Christian, Ebner Florian H, Schittenhelm Jens

Abstract excerpt

AIMS: The zinc finger transcription factor WT1 is expressed in astrocytic neoplasms and therefore is a potential target of immunotherapy in brain tumours. Our aim was to further elucidate the role of WT1 as a diagnostic and prognostic marker in neuropathology, particularly as to the differentiation of astrocytoma from oligodendroglioma as well as to the dependency of WT1 expression on clinically relevant...

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Share to Astrocytoma
Share to DNA Modification Methylases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24607494
DOI: 10.1136/jclinpath-2013-202114

Genes

IDH1
MGMT

Provenance

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