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Detection of protamine 2 in bovine spermatozoa and testicles

28 Mar 2019

Abstract excerpt

BACKGROUND: Sperm DNA integrity is crucial for transmission of genetic information to future generations and DNA damage can occur during chromatin packaging. Chromatin packaging involves the replacement of somatic nucleosomal histones by nuclear proteins called protamines. Protamine 1 (PRM1) is transcribed and translated in spermatids of all mammals; however, protamine 2 (PRM2) is transcribed in low levels in...

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PMID: 30920782
DOI: 10.1111/andr.12610

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