Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Blood cytokine patterns suggest a modest inflammation phenotype in subjects with long-chain fatty acid oxidation disorders.

Physiological reports - 1 Mar 2019

McCoin Colin S, Gillingham Melanie B, Knotts Trina A, Vockley Jerry, Ono-Moore Kikumi D, Blackburn Michael L, Norman Jennifer E, Adams Sean H

Abstract excerpt

Excessive cellular accumulation or exposure to lipids such as long-chain acylcarnitines (LCACs), ceramides, and others is implicated in cell stress and inflammation. Such a situation might manifest when there is a significant mismatch between long-chain fatty acid (LCFA) availability versus storage and oxidative utilization; for example, in cardiac ischemia, increased LCACs may contribute to tissue cell stress...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carnitine O-Palmitoyltransferase
Share to Exercise

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Inflammation Mediators

Share to Interferon-gamma

Share to Interleukin-10

Share to Interleukin-8

Share to Lipid Metabolism, Inborn Errors

Share to Postprandial Period

Source

Open in PubMed Open full text

Identifiers

PMID: 30912279
DOI: 10.14814/phy2.14037
PMCID: PMC6434073

Genes

CPT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Blood cytokine patterns suggest a modest inflammation phenotype in subjects with long-chain fatty acid oxidation disorders.PMID 30912279Read ↗

Multi-omics provide evidence for an anti-inflammatory immune signature and metabolic alterations in patients with Long COVID Syndrome – an exploratory studySemantic proximity Read ↗

Multi-Omics Provide Evidence for an Anti-Inflammatory Immune Signature and Metabolic Alterations in Patients with Long COVID Syndrome – an Exploratory StudySemantic proximity Read ↗

Inflammation, physical activity, and chronic disease: An evolutionary perspectiveSemantic proximity Read ↗

Combination of lipid metabolism alterations and their sensitivity to inflammatory cytokines in human lipin-1-deficient myoblasts.Semantic proximity Read ↗

Cytokines as Potential Novel Therapeutic Targets in Severe Inflammatory CardiomyopathySemantic proximity Read ↗

Immunometabolism at the Heart of Cardiovascular DiseaseSemantic proximity Read ↗

Fatty Acids and Their Roles in Cardiac Physiology and Pathology: Mechanistic and Interventional StudiesSemantic proximity Read ↗

Fatty Acids and Their Roles in Cardiac Physiology and Pathology: Mechanistic and Interventional StudiesSemantic proximity Read ↗

Innate immune remodeling by short‐term intensive fastingSemantic proximity Read ↗

Fatty acids, monocytes and ageingSemantic proximity Read ↗

IL-10 constrains sphingolipid metabolism via fatty acid desaturation to limit inflammationSemantic proximity Read ↗

The true cost of in-patient obesity: impact of obesity on inflammatory stress and morbidity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.