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Article

GSTP1 as a potential predictive factor for adverse events associated with platinum‑based antitumor agent‑induced peripheral neuropathy

8 Jan 2019

Abstract excerpt

Glutathione S‑transferase (GST) exhibits antidotal effects on numerous drugs, including platinum‑based antineoplastic drugs. Furthermore, GST Pi 1 (GSTP1) polymorphism is associated with peripheral neuropathy. In the present study, it was determined whether GSTP1 can predict adverse events associated with platinum‑based antitumor agent‑induced peripheral neuropathy among Japanese patients. The subjects included...

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Identifiers

PMID: 30854066
DOI: 10.3892/ol.2019.9907

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