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Exploiting DNA repair defects in triple negative breast cancer to improve cell killing

1 Jan 2020

Abstract excerpt

BACKGROUND: The lack of molecular targets for triple negative breast cancer (TNBC) has limited treatment options and reduced survivorship. Identifying new molecular targets may help improve patient survival and decrease recurrence and metastasis. As DNA repair defects are prevalent in breast cancer, we evaluated the expression and repair capacities of DNA repair proteins in preclinical models. METHODS: DNA repair...

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PMID: 32994807
DOI: 10.1177/1758835920958354

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