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Article

The Epstein-Barr virus EBNA1 protein modulates the alternative splicing of cellular genes

4 Mar 2019

Abstract excerpt

BACKGROUND: Alternative splicing (AS) is an important mRNA maturation step that allows increased variability and diversity of proteins in eukaryotes. AS is dysregulated in numerous diseases, and its implication in the carcinogenic process is well known. However, progress in understanding how oncogenic viruses modulate splicing, and how this modulation is involved in viral oncogenicity has been limited....

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PMID: 30832682
DOI: 10.1186/s12985-019-1137-5

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