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Article

Plasma sphingolipids associated with chronic obstructive pulmonary disease phenotypes.

American journal of respiratory and critical care medicine - 1 Feb 2015

Bowler Russell P, Jacobson Sean, Cruickshank Charmion, Hughes Grant J, Siska Charlotte, Ory Daniel S, Petrache Irina, Schaffer Jean E, Reisdorph Nichole, Kechris Katerina

Abstract excerpt

RATIONALE: Chronic obstructive pulmonary disease (COPD) occurs in a minority of smokers and is characterized by intermittent exacerbations and clinical subphenotypes such as emphysema and chronic bronchitis. Although sphingolipids as a class are implicated in the pathogenesis of COPD, the particular sphingolipid species associated with COPD subphenotypes remain unknown. OBJECTIVES: To use mass spectrometry to...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25494452
DOI: 10.1164/rccm.201410-1771OC
PMCID: PMC4351578

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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